Josef Köhrle Selected Research

Allan-Herndon-Dudley syndrome

7/2016	Few Amino Acid Exchanges Expand the Substrate Spectrum of Monocarboxylate Transporter 10.
9/2015	High T3, Low T4 Serum Levels in Mct8 Deficiency Are Not Caused by Increased Hepatic Conversion through Type I Deiodinase.
10/2011	Monocarboxylate transporter 8 deficiency: altered thyroid morphology and persistent high triiodothyronine/thyroxine ratio after thyroidectomy.
3/2011	Developmental and cell type-specific expression of thyroid hormone transporters in the mouse brain and in primary brain cells.
9/2010	Essential molecular determinants for thyroid hormone transport and first structural implications for monocarboxylate transporter 8.

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Josef Köhrle Research Topics

Disease

16	Neoplasms (Cancer) 01/2018 - 08/2002
14	Body Weight (Weight, Body) 01/2022 - 06/2007
14	Hyperthyroidism 01/2022 - 12/2013
12	Thyroid Neoplasms (Thyroid Cancer) 11/2015 - 08/2002
8	Hypothyroidism 05/2022 - 10/2002
6	Thyroid Diseases (Thyroid Disease) 01/2019 - 10/2013
6	Goiter 10/2015 - 08/2002
6	Carcinoma (Carcinomatosis) 05/2005 - 08/2002
5	Sepsis (Septicemia) 01/2019 - 01/2008
5	Allan-Herndon-Dudley syndrome 07/2016 - 09/2010
4	Obesity 01/2021 - 01/2015
4	Critical Illness (Critically Ill) 12/2016 - 04/2002
4	Graves Disease (Basedow Disease) 10/2015 - 02/2013
3	Thyrotoxicosis 01/2020 - 10/2016
3	Insulin Resistance 12/2019 - 09/2015
3	Type 2 Diabetes Mellitus (MODY) 01/2018 - 07/2013
3	Hepatocellular Carcinoma (Hepatoma) 01/2017 - 11/2012
3	Inflammation (Inflammations) 09/2015 - 05/2010
3	Follicular Adenocarcinoma 08/2010 - 04/2004
3	Seizures (Absence Seizure) 03/2010 - 07/2004
3	Carcinogenesis 09/2009 - 01/2003
2	Cachexia 01/2019 - 11/2012
2	Atrial Fibrillation 01/2019 - 06/2015
2	Cardiovascular Diseases (Cardiovascular Disease) 10/2016 - 09/2014
2	Hyperlipidemias (Hyperlipidemia) 10/2016 - 01/2015
2	Atherosclerosis 10/2016 - 10/2014
2	Autoimmune Thyroiditis (Lymphomatous Thyroiditis) 10/2015 - 10/2013
2	Hashimoto Disease (Thyroiditis, Hashimoto) 10/2015 - 11/2014
2	Graves Ophthalmopathy 11/2014 - 02/2013
2	Fibrosis (Cirrhosis) 02/2012 - 10/2011
2	Thyroid Nodule (Nodule, Thyroid) 04/2011 - 12/2006
2	Intellectual Disability (Idiocy) 03/2011 - 12/2009
2	Adenoma (Adenomas) 08/2010 - 01/2003
2	Ataxia (Dyssynergia) 03/2010 - 02/2008
2	Congenital Hypothyroidism (Cretinism) 12/2009 - 10/2002
2	Anaplastic Thyroid Carcinoma 04/2004 - 08/2002
2	Colonic Neoplasms (Colon Cancer) 01/2004 - 01/2003
1	Periventricular Nodular Heterotopia 08/2021
1	Non-alcoholic Fatty Liver Disease 01/2021
1	Hyperplasia 12/2020
1	Hypertrophy 12/2020
1	Heart Failure 01/2019
1	Weight Loss (Weight Reduction) 01/2019
1	Melanoma (Melanoma, Malignant) 01/2018
1	Hyperglycemia 01/2018
1	Uveal melanoma 01/2018
1	Pre-Eclampsia (Preeclampsia) 01/2018
1	Kidney Neoplasms (Kidney Cancer) 01/2017

Drug/Important Bio-Agent (IBA)

23	Thyroid HormonesIBA 08/2021 - 10/2002
17	SeleniumIBA 10/2015 - 09/2002
11	Thyroxine (Levothyroxine)FDA LinkGeneric 05/2022 - 04/2002
11	Iodide Peroxidase (Deiodinase)IBA 01/2022 - 04/2002
11	Messenger RNA (mRNA)IBA 01/2018 - 06/2003
9	3,5-diiodothyronineIBA 01/2021 - 09/2014
9	Selenoprotein PIBA 10/2015 - 09/2002
8	Triiodothyronine (Liothyronine)FDA LinkGeneric 05/2022 - 04/2002
7	Biomarkers (Surrogate Marker)IBA 01/2020 - 06/2004
7	Proteins (Proteins, Gene)FDA Link 01/2020 - 09/2002
6	Selenoproteins (Selenoprotein)IBA 03/2010 - 01/2004
5	Hormones (Hormone)IBA 01/2021 - 07/2010
5	3-iodothyronamineIBA 01/2019 - 01/2015
5	IodineIBA 09/2015 - 10/2002
4	Pharmaceutical PreparationsIBA 01/2021 - 12/2017
4	Trace Elements (Biometals)IBA 10/2013 - 01/2004
4	EnzymesIBA 08/2010 - 04/2002
4	Glutathione PeroxidaseIBA 08/2005 - 01/2003
3	AntibodiesIBA 11/2017 - 02/2013
3	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 12/2016 - 06/2004
3	Tretinoin (Retinoic Acid)FDA LinkGeneric 08/2010 - 04/2004
2	Amitrole (Aminotriazole)IBA 01/2022 - 08/2021
2	ProteomeIBA 01/2021 - 01/2017
2	ThyroninesIBA 12/2019 - 01/2017
2	Drinking WaterIBA 11/2017 - 09/2015
2	Oncogene Proteins (Oncogene Protein)IBA 01/2017 - 03/2009
2	Adrenergic Agents (Adrenergic Drugs)IBA 12/2016 - 09/2015
2	Selenium CompoundsIBA 10/2015 - 10/2013
2	Propylthiouracil FDA Link 08/2015 - 12/2013
2	CreatinineIBA 11/2014 - 12/2006
2	ProcalcitoninIBA 05/2011 - 09/2010
2	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2011 - 01/2004
2	RacivirIBA 10/2004 - 08/2002
1	MonoiodotyrosineIBA 01/2022
1	PesticidesIBA 08/2021
1	Food Additives (Food Additive)IBA 12/2020
1	Monoclonal AntibodiesIBA 01/2019
1	IsoflavonesIBA 01/2018
1	Liver GlycogenIBA 01/2018
1	RelaxinIBA 01/2018
1	C-PeptideIBA 01/2018
1	inhibin AIBA 01/2018
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2018
1	EndoglinIBA 01/2018
1	Phosphates (Orthophosphate)IBA 11/2017
1	Bone Density Conservation AgentsIBA 11/2017
1	Diphosphonates (Bisphosphonates)IBA 11/2017
1	Zoledronic Acid (Zometa)FDA Link 11/2017
1	AminoglycosidesIBA 01/2017
1	antibiotic G 418IBA 01/2017

Therapy/Procedure

8	Therapeutics 05/2022 - 04/2004
4	Thyroidectomy 01/2019 - 06/2004